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laryngeal carcinoma

Laryngeal carcinoma is one of the most common head and neck tumours with an annual incidence of approximately 1 per 100,000. It should be suspected in any patient with hoarseness of the voice for three weeks or longer until proven otherwise.

Men are affected more often than women but during the last decade, the number of cases in women has increased such that they now account for about 20% of cases. Most patients are elderly and almost always, are smokers.

Other features of laryngeal cancer include:

  • sixty percent of tumours occur in the glottis and present early with dysphonia
    • glottic cancer has the most favourable prognosis of all forms of laryngeal cancer, as people tend to seek medical advice for chronic hoarseness, which is the most common early symptom
  • other symptoms of laryngeal cancer may include pain or problems with swallowing (dysphagia). There can also be a lump in the neck, sore throat, earache, or a persistent cough.
  • virtually all cancer of the larynx is squamous cell carcinoma.
  • if detected early, the prognosis is excellent with a 90% 5 year cure rate
    • overall survival rates are better than for oral or pharyngeal cancer, with nearly two-thirds of patients surviving for five years (2)

Reference:

  1. Referral Guidelines for Suspected Cancer (April 2000). NHS Executive.
  2. NICE (2004). Improving the outcomes in head and neck cancers - the manual

The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2001 Oxbridge Solutions Limited™. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd does not receive income from sponsorship or advertising.