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prostatic carcinoma

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Prostate carcinoma is considered to be a spectrum of diseases which may vary from slow growing tumours (which are often asymptomatic) to very aggressive tumours (1).

  • it is the most common cancer in men in the UK
  • is largely a disease of older men and is rare before 50 years (1)
  • prostate cancer is the most common cancer in men and makes up 26% of all male cancer diagnoses in the UK (2)
    • in 2008, 34,335 men were diagnosed with prostate cancer and there were 9376 deaths from prostate cancer in England, Wales and Northern Ireland. This figure increased to 9632 deaths in 2010

  • prostate cancer is predominantly a disease of older men (aged 65-79 years) but around 25% of cases occur in men younger than 65
    • also a higher incidence of and mortality from prostate cancer in men of black African-Caribbean family origin compared with white Caucasian men.

Prostate tumours can be divided into:

  • localised prostate cancer
    • the tumour is confined to the capsule of the gland
    • grows slowly and usually remains asymptomatic (1)
  • locally advanced prostate cancer
    • cancers have extended outside the prostatic capsule
    • frequently asymptomatic
  • metastatic prostate cancer
    • may be the first sign of prostate cancer
    • frequently spreads to the bone and causes pain
    • majority die due to the metastatic disease
    • 5-year survival rate  is approximately 30% (1)

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