Prostate carcinoma is considered to be a spectrum of diseases which may vary from slow growing tumours (which are often asymptomatic) to very aggressive tumours (1).
- it is the most common cancer in men in the UK
- is largely a disease of older men and is rare before 50 years (1)
- prostate cancer is the most common cancer in men and makes up 26%
of all male cancer diagnoses in the UK (2)
- in 2008, 34,335 men were diagnosed with prostate cancer and there were
9376 deaths from prostate cancer in England, Wales and Northern Ireland.
This figure increased to 9632 deaths in 2010
- in 2008, 34,335 men were diagnosed with prostate cancer and there were 9376 deaths from prostate cancer in England, Wales and Northern Ireland. This figure increased to 9632 deaths in 2010
- prostate cancer is predominantly a disease of older men (aged 65-79 years)
but around 25% of cases occur in men younger than 65
- also a higher incidence of and mortality from prostate cancer in men of black African-Caribbean family origin compared with white Caucasian men.
Prostate tumours can be divided into:
- localised prostate cancer
- the tumour is confined to the capsule of the gland
- grows slowly and usually remains asymptomatic (1)
- locally advanced prostate cancer
- cancers have extended outside the prostatic capsule
- frequently asymptomatic
- metastatic prostate cancer
- may be the first sign of prostate cancer
- frequently spreads to the bone and causes pain
- majority die due to the metastatic disease
- 5-year survival rate is approximately 30% (1)