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Bipolar affective disorder is a condition where there are periodic swings of
mood periods of months or years between manic episodes and depressed episodes. The
American Psychiatric Association's Diagnostic and Statistical Manual (DSM-IV)
distinguishes between bipolar I and bipolar II disorder: - Bipolar I
disorder:
- lifetime prevalence of around 0.4-1.6%
- characterised
by episodes of depression, mania or mixed states separated by periods of normal
mood
- features of mania include elevated, expansive, euphoric mood, irritability
and hyperactivity, decreased need for sleep, disorganised behaviour, delusions,
hallucinations and significant (often severe) functional impairment
- Bipolar
II disorder
- lifetime prevalence around 0.5%
- do not experience
mania but have periods of hypomania, depression or mixed states
- hypomania,
as defined by DSM-IV, is characterised by milder elevation of mood and overactivity
(lasting at least 4 days) without psychotic features or significant functional
impairment
In both bipolar I and bipolar II disorder,
depression tends to predominate over elevated mood in the overall course of the
illness Note also that at some stage in their illness, around 14-53% of
patients are reported to develop 'rapid cycling' - defined as four or more manic,
hypomanic, depressive or mixed episodes occurring within 12 months. Reference: - Drug
and Therapeutics Bulletin 2005; 43(4):28-31.
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