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bipolar affective disorder

 
   

Bipolar affective disorder is a condition where there are periodic swings of mood periods of months or years between manic episodes and depressed episodes.

The American Psychiatric Association's Diagnostic and Statistical Manual (DSM-IV) distinguishes between bipolar I and bipolar II disorder:

  • Bipolar I disorder:
    • lifetime prevalence of around 0.4-1.6%
    • characterised by episodes of depression, mania or mixed states separated by periods of normal mood
      • features of mania include elevated, expansive, euphoric mood, irritability and hyperactivity, decreased need for sleep, disorganised behaviour, delusions, hallucinations and significant (often severe) functional impairment
  • Bipolar II disorder
    • lifetime prevalence around 0.5%
    • do not experience mania but have periods of hypomania, depression or mixed states
      • hypomania, as defined by DSM-IV, is characterised by milder elevation of mood and overactivity (lasting at least 4 days) without psychotic features or significant functional impairment

In both bipolar I and bipolar II disorder, depression tends to predominate over elevated mood in the overall course of the illness

Note also that at some stage in their illness, around 14-53% of patients are reported to develop 'rapid cycling' - defined as four or more manic, hypomanic, depressive or mixed episodes occurring within 12 months.

Reference:

  1. Drug and Therapeutics Bulletin 2005; 43(4):28-31.

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