This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Globoid cell leukodystrophy

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Krabbe's disease is an autosomal recessive disease caused by a deficiency of galactocerebroside B galactosidase which results in an accumulation of galactocerebroside.

The patient presents in the first 6 months of life with:

  • rigidity
  • instability
  • decreased alertness

Later, the child becomes blind and deaf.

The disease is fatal within a year.

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page