Erythema nodosum is a panniculitis - an inflammation of the fat, seen principally in adult females. The female to male ratio is five to one but in children the ratio is 1:1

The disease can be seen at any age with a peak incidence between the ages of 20 and 30 years (1).

The manifestation is with red nodules - in the literal translation of the name - most often seen symmetrically over the shins (1).

Click here for an example image of this condition

Reference:

• (1) Schwarts RA, Nervi SJ. Erythema Nodosum: A Sign of Systemic Disease. AFP 2007;75(5)