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multiple myeloma
 
   

A multiple myeloma is a malignant neoplasm of plasma cells that arises in the bone marrow. Presentation is with anaemia, bone pain, skeletal destruction, pathologic fractures, or Bence Jones proteinuria.

In the majority of cases, complete immunoglobulins are secreted together with an excess of Ig fragments. In up to one quarter of cases, Ig fragments only occur and the condition is referred to as light chain disease or Bence Jones myeloma.

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