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In the UK, up to 33% of women have polycystic ovaries (i.e. 10 or more follicles
per ovary detected on ultrasound).
Of these, an estimated 33% have polycystic ovarian syndrome (PCOS), generally
defined in the UK as polycystic ovaries together with one or more characteristic
features (hirsutism, acne, male-pattern baldness, amenorrhoea or oligomenorrhoea,
or raised serum concentrations of testosterone and/or luteinising hormone) .
In polycystic ovarian syndrome the associated metabolic abnormalities (abnormal
serum lipid concentrations and insulin resistance) also put some women at an
increased risk of developing diabetes mellitus (1)
| NICHD (1990) Diagnostic Criteria for PCOS is: |
| Clinical Hyperandrogenism (Ferriman-Gallwey Score >8) or Biochemical
Hyperandrogenism (Elevated Total/Free Testosterone) AND |
| Oligomenorrhea (Less Than 6-9 Menses per Year) or Oligo-Ovulation AND |
| Polycystic Ovaries on Ultrasound (>= 12 Antral Follicles in One Ovary
or Ovarian Volume >= 10 cm3) |
| Rotterdam (2003) Diagnostic criteria for PCOS - two out of three of: |
| Clinical Hyperandrogenism (Ferriman-Gallwey Score >8) or Biochemical
Hyperandrogenism (Elevated Total/Free Testosterone) OR |
| Oligomenorrhea (Less Than 6-9 Menses per Year) or Oligo-Ovulation OR |
| Polycystic Ovaries on Ultrasound (>= 12 Antral Follicles in One Ovary
or Ovarian Volume >= 10 cm3) |
| AE-PCOS Society (2009) Diagnostic Criteria for PCOS is: |
| Clinical Hyperandrogenism (Ferriman-Gallwey Score >8) or Biochemical
Hyperandrogenism (Elevated Total/Free Testosterone) PLUS Either of: |
| Oligomenorrhea (Less Than 6-9 Menses per Year) or Oligo-Ovulation OR |
| Polycystic Ovaries on Ultrasound (>= 12 Antral Follicles in One Ovary
or Ovarian Volume >= 10 cm3) |
Thyroid dysfunction, congenital adrenal hyperplasia, hyperprolactinaemia, androgen-secreting
tumours and Cushing’s syndrome must to be excluded before making a diagnosis
of PCOS (1).
Reference:
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