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polycystic ovarian syndrome
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In the UK, up to 33% of women have polycystic ovaries (i.e. 10 or more follicles per ovary detected on ultrasound).

Of these, an estimated 33% have polycystic ovarian syndrome (PCOS), generally defined in the UK as polycystic ovaries together with one or more characteristic features (hirsutism, acne, male-pattern baldness, amenorrhoea or oligomenorrhoea, or raised serum concentrations of testosterone and/or luteinising hormone) .

In polycystic ovarian syndrome the associated metabolic abnormalities (abnormal serum lipid concentrations and insulin resistance) also put some women at an increased risk of developing diabetes mellitus (1)

NICHD (1990) Diagnostic Criteria for PCOS is:
Clinical Hyperandrogenism (Ferriman-Gallwey Score >8) or Biochemical Hyperandrogenism (Elevated Total/Free Testosterone) AND
Oligomenorrhea (Less Than 6-9 Menses per Year) or Oligo-Ovulation AND
Polycystic Ovaries on Ultrasound (>= 12 Antral Follicles in One Ovary or Ovarian Volume >= 10 cm3)

 

Rotterdam (2003) Diagnostic criteria for PCOS - two out of three of:
Clinical Hyperandrogenism (Ferriman-Gallwey Score >8) or Biochemical Hyperandrogenism (Elevated Total/Free Testosterone) OR
Oligomenorrhea (Less Than 6-9 Menses per Year) or Oligo-Ovulation OR
Polycystic Ovaries on Ultrasound (>= 12 Antral Follicles in One Ovary or Ovarian Volume >= 10 cm3)

 

AE-PCOS Society (2009) Diagnostic Criteria for PCOS is:
Clinical Hyperandrogenism (Ferriman-Gallwey Score >8) or Biochemical Hyperandrogenism (Elevated Total/Free Testosterone) PLUS Either of:
Oligomenorrhea (Less Than 6-9 Menses per Year) or Oligo-Ovulation OR
Polycystic Ovaries on Ultrasound (>= 12 Antral Follicles in One Ovary or Ovarian Volume >= 10 cm3)

Thyroid dysfunction, congenital adrenal hyperplasia, hyperprolactinaemia, androgen-secreting tumours and Cushing’s syndrome must to be excluded before making a diagnosis of PCOS (1).

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