QUICKmedicine app

2,3 DPG

FREE subscriptions for doctors and students... click here
You have 3 open access pages.


2,3-diphosphoglycerate lowers the affinity of haemoglobin A for oxygen by binding to and stabilising deoxyhaemoglobin.

Hypoxia e.g. due to lung disease or high altitude, results in an adaptive rise in the concentrations of 2,3-DPG and an improvement in the quantity of oxygen delivered to the tissues.