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Anemia (macrocytic with normoblastic bone marrow)

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Macrocytic anaemia with a normoblastic bone marrow presents as round macrocytes on the blood film.

Possible causes include:

  • alcohol
  • liver cirrhosis
  • reticulocytosis
  • marrow infiltration
  • hypothyroidism / myxoedema
  • myleloproliferative disease
  • myelodysplastic syndrome
  • acquired sideroblastic anaemia

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