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reference range (FSH)

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IU/L

  • <1-3 prepubertal
  • 1-8 males
  • 1-11 females; follicular and luteal phase
  • 6-26 at ovulation
  • 30-118 post-menopausal

Note that reference ranges may vary between laboratories.

NICE state that with respect to the menopause and perimenopause (1):

  • diagnose the following without laboratory tests in otherwise healthy women aged over 45 years with menopausal symptoms:

    • perimenopause based on vasomotor symptoms and irregular periods
    • menopause in women who have not had a period for at least 12 months and are not using hormonal contraception
    • menopause based on symptoms in women without a uterus

  • FSH test:

    • do not use a serum follicle-stimulating hormone (FSH) test to diagnose menopause in women using combined oestrogen and progestogen contraception or high-dose progestogen

    • consider using a FSH test to diagnose menopause only:
      • in women aged 40 to 45 years with menopausal symptoms, including a change in their menstrual cycle

      • n women aged under 40 years in whom menopause is suspected

        • diagnose premature ovarian insufficiency in women aged under 40 years based on:
          • menopausal symptoms, including no or infrequent periods (taking into account whether the woman has a uterus) and
          • elevated FSH levels on 2 blood samples taken 4-6 weeks apart

Reference:

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