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linitis plastica

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A leather bottle stomach - linitis plastica - describes a stomach that has a gastric carcinoma which is morphologically an infiltrating carcinoma.

Infiltrating carcinomas of the stomach tend to occur in younger patients and carry a poorer prognosis than other morphological types.

Infiltrating carcinomas cause a leather bottle stomach as a result of spreading widely beneath the stomach mucosa and invading the muscular wall. This pattern of 'growth' causes thickening and stiffening of the stomach wall. As a result the stomach also has a reduced capacity. The resultant stiff-walled, smaller capacity stomach is much akin to a leather bottle.

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