aspartate aminotransferase - General Practice Notebook

aspartate aminotransferase

Aspartate aminotransferase is an enzyme found in heart, liver, skeletal muscle, pancreas, kidney and red blood cells. It is an aminotransferase, transferring an amino group to ketoacids. It requires pyridoxal-5-phosphate as a coenzyme. Increased plasma activity is the result of leakage of enzyme from tissues as a result of cellular damage: it is found predominantly in the cytoplasm and mitochondria.

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AST in myocardial disease
reference range (AST)
AST in liver disease
AST in skeletal muscle disease
AST in other disease
aminotransferases
asymptomatic raised aminotransferase levels
AST : ALT ratio

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