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Most prominent signs according to age of individual with Klinefelter's syndrome

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

most prominent signs according to period of life in patients with Klinefelter’s syndrome

Birth

  • cryptorchidism
  • small penis
  • scrotum bifidus
  • hypospadia
  • fifth finger clinodactily
  • cleft palate
  • inguinal hernia
  • hypotonia

Infancy

  • small testes
  • small penis size
  • speech and language deficits
  • long legs and arms

Childhood

  • speech and language deficits
  • learning disabilities
  • psychological difficulties
  • behavioral issues

Puberty

  • long legs and arms
  • gynaecomastia
  • sparse facial, body and pubic hair
  • gradual increase of FSH and LH

Adulthood

  • small and firm testes
  • gynaecomastia
  • sparse facial, body and pubic hair
  • infertility
  • sexual dysfunction
  • metabolic syndrome

Reference:

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