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familial cancer syndromes causing sarcomas

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Soft tissue sarcomata are rare tumours accounting for less than 1% of adult tumours but up to 6% of childhood tumours.

A genetic risk factor for sarcoma formation may be present in as many as one third of all patients with childhood sarcomata.

Familial syndromes causing sarcomata include:

  • neurofibromatosis
  • familial retinoblastoma
  • Li-Fraumeni syndrome
  • Beckwith-Wiedemann syndrome
  • basal cell naevus
  • Gardner syndrome

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