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Kveim test

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This is a test for sarcoidosis. An extract of sarcoid involved spleen is injected intradermally and 4-6 weeks later a skin nodule appears which is biopsied and examined for evidence of granuloma formation (1).

  • this is a highly specific test and is positive in 80% of patients with the disease.

A positive result is less likely if there is no lymph node involvement, the disease is of long standing, or the patient is receiving steroid therapy.

A positive result may also occur in other diseases with enlarged lymph nodes, for example, tuberculosis and leukaemia.

Test not now used because of risk of infection.



General Practice Notebook
General Practice Notebook
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