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Frohlich's adiposogenital syndrome

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Frohlich's adiposogenital syndrome seen in boys and is characterized by obesity and hypogonadotropic hypogonadism. There is delayed skeletal maturation.

Variable features in this syndrome include:

  • diabetes insipidus
  • visual impairment
  • mental retardation

Patients with this condition may present with a slipped upper femoral epiphysis. They are likely to be fat and short.

The anterior pituitary is usually unaffected in these patients. The syndrome is believed to be a result of hypothalamic dysfunction.


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